A Functionally Conserved Enhancer is Critical for PGC1A Expression and Thermogenesis in Brown Fat

ABSTRACT Brown adipose tissue (BAT) undergoes progressive age‐related involution into white adipose tissue (WAT), yet the epigenetic mechanisms underlying BAT whitening remain unclear. This study investigates the transcriptomic dynamics of goat perirenal adipose tissue (PRAT) across four postnatal s...

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Detalhes bibliográficos

Principais autores:	Duo Su, Haosen Yang, Xiaokai Li, Tingting Jiang, Siyuan Zhan, Tao Zhong, Jiazhong Guo, Yan Wang, Li Li, Hongping Zhang, Linjie Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2026-06-01
coleção:	Advanced Science
Assuntos:	brown adipose tissue conserved enhancer epigenomics PGC1A transcription regulation thermogenesis
Acesso em linha:	https://doi.org/10.1002/advs.202518153
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