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Prognostic impact of mRNA levels of LGR5 transcript variants in OSCC patients

Abstract Background The human leucine-rich, repeat-containing G protein-coupled receptor 5 (LGR5) is a stem cell marker in numerous adult tissues and is overexpressed in a large number of human carcinoma including colon cancer, breast cancer and oral squamous cell carcinomas (OSCC). The role of the...

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Guardado en:
Autores principales: Swetlana Rot, Tom Kaune, Helge Taubert, Thomas Greither, Johanna Kotrba, Antje Güttler, Henri Wichmann, Udo Bilkenroth, Andreas Wienke, Bilal Al-Nawas, Matthias Bache, Dirk Vordermark, Claudia Wickenhauser, Daniel Bethmann, Alexander W. Eckert, Matthias Kappler
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2019-02-01
Colección:BMC Cancer
Materias:
Head and neck squamous cell carcinoma, overall survival, stem cell-associated gene
LGR5
Splice variants
EMT
Acceso en línea:http://link.springer.com/article/10.1186/s12885-019-5327-8
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