TGF-β promotes survival on mesencephalic dopaminergic neurons in cooperation with Shh and FGF-8

Impaired neuronal survival is a key event in the development of degenerative diseases, such as Parkinson's disease (PD). Here we show that transforming growth factor beta (TGF-β) acts directly on rat E14 midbrain dopaminergic neurons in vitro, its survival-promoting effect being not mediated by BDNF...

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Auteurs principaux:	Eleni Roussa, Lilla M Farkas, Kerstin Krieglstein
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2004-07-01
Collection:	Neurobiology of Disease
Sujets:	Neurotrophins GDNF FGF2 Neurotrophic function Proliferation Phenotype induction
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S0969996104000646
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