Emergence of ceftazidime-avibactam resistance due to a novel blaKPC-2 mutation during treatment of carbapenem-resistant Klebsiella pneumoniae infections

Objective: Klebsiella pneumoniae carbapenemase (KPC)-producing K.pneumoniae has represented a serious health problem in worldwide. The resistance to ceftazidime-avibactam (CAZ-AVI) began to emerge since its approval in 2015. We aim to explore the resistance mechanism of CAZ-AVI. Methods: Phenotypic...

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Hlavní autoři:	Quanfeng Liao, Jin Deng, Yu Feng, Weili Zhang, Siying Wu, Ya Liu, Huijuan Che, Yi Xie
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2022-05-01
Edice:	Journal of Infection and Public Health
Témata:	CAZ-AVI resistance Carbapenem-resistant Klebsiella pneumoniae Mutant KPC carbapenemase
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S1876034122000855
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