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Single-cell RNA sequencing reveals that Danggui Buxue Tang decoction facilitates wound healing after anal fistula by promoting M2 macrophage polarization

Abstract Background We aim to employ single-cell RNA (scRNA) sequencing technology to investigate potential regulatory mechanism of Danggui Buxue Tang (DBT) in wound healing for its utilization in post-anal fistula surgery recovery. Methods Fistula-like wound model in mice was established and admini...

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Wedi'i Gadw mewn:
Prif Awduron: Xue Pang, Yutao Wang, Jianzhuang Guo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMC 2025-10-01
Cyfres:Hereditas
Pynciau:
Danggui buxue tang
Macrophages
Anal fistula
Single cell RNA sequencing
Anti-inflammation
Mynediad Ar-lein:https://doi.org/10.1186/s41065-025-00578-2
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