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The flavonoid luteolin worsens chemical-induced colitis in NF-kappaB(EGFP) transgenic mice through blockade of NF-kappaB-dependent protective molecules.

The flavonoid luteolin has anti-inflammatory properties both in vivo and in vitro. However, the impact of luteolin on experimental models of colitis is unknown.To address the therapeutic impact of luteolin, NF-kappaB(EGFP) transgenic mice were fed a chow diet containing 2% luteolin- or isoflavone-fr...

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Principais autores: Thomas Karrasch, Joo-Sung Kim, Byung Ik Jang, Christian Jobin
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2007-07-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC1895919?pdf=render
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