Scaffold-Based (Matrigel™) 3D Culture Technique of Glioblastoma Recovers a Patient-like Immunosuppressive Phenotype

Conventional 2D cultures are commonly used in cancer research though they come with limitations such as the lack of microenvironment or reduced cell heterogeneity. In this study, we investigated in what respect a scaffold-based (Matrigel™) 3D culture technique can ameliorate the limitations of 2D cu...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Frank K. Braun, Tanja Rothhammer-Hampl, Julia Lorenz, Sandra Pohl, Ayse-Nur Menevse, Arabel Vollmann-Zwerenz, Elisabeth Bumes, Maren Büttner, Saida Zoubaa, Martin Proescholdt, Nils O. Schmidt, Peter Hau, Philipp Beckhove, Beate Winner, Markus J. Riemenschneider
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2023-07-01
coleção:	Cells
Assuntos:	brain cancer tumor organoids GBM next-generation sequencing single-cell RNA sequencing
Acesso em linha:	https://www.mdpi.com/2073-4409/12/14/1856
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!