Genetic Alterations in Renal Cancers: Identification of The Mechanisms Underlying Cancer Initiation and Progression and of Therapeutic Targets

Renal cell cancer (RCC) involves three most recurrent sporadic types: clear-cell RCC (70–75%, CCRCC), papillary RCCC (10–15%, PRCC), and chromophobe RCC (5%, CHRCC). Hereditary cases account for about 5% of all cases of RCC and are caused by germline pathogenic variants. Herein, we review how a bett...

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Bibliografische gegevens

Hoofdauteurs:	Ugo Testa, Elvira Pelosi, Germana Castelli
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	MDPI AG 2020-07-01
Reeks:	Medicines
Onderwerpen:	renal cell cancer genomic landscape targeted therapy tumor evolution tumor heterogeneity
Online toegang:	https://www.mdpi.com/2305-6320/7/8/44
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