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Palmitoylation of CLDN12 regulated by ZDHHC7 and APT1/2 promotes hepatitis C virus entry

ABSTRACT Hepatitis C virus (HCV) entry is a critical step in establishing infection and is highly dependent on host cell co-receptors. We previously identified that the tight junction protein CLDN12 facilitates HCV entry. However, the regulatory mechanisms governing the dynamic post-translational mo...

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Principais autores: Huiying Zhang, Yihan Liu, Ting Xu, Junwen Luan, Leiliang Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2026-07-01
coleção:Journal of Virology
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Acesso em linha:https://journals.asm.org/doi/10.1128/jvi.00638-26
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