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Identification of KCC2 Mutations in Human Epilepsy Suggests Strategies for Therapeutic Transporter Modulation

Epilepsy is a common neurological disorder characterized by recurrent and unprovoked seizures thought to arise from impaired balance between neuronal excitation and inhibition. Our understanding of the neurophysiological mechanisms that render the brain epileptogenic remains incomplete, reflected by...

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Principais autores: Phan Q. Duy, Wyatt B. David, Kristopher T. Kahle
格式: Artigo
语言:Inglês
出版: Frontiers Media S.A. 2019-11-01
丛编:Frontiers in Cellular Neuroscience
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在线阅读:https://www.frontiersin.org/article/10.3389/fncel.2019.00515/full
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