CD38-targeted therapy with daratumumab reduces autoantibody levels in multiple myeloma patients
Autoantibody-producing plasma cells are frequently resistant to conventional immunosuppressive treatments and B-cell depletion therapy. As a result of this resistance, autoreactive plasma cells survive conventional therapy, resulting in persistent autoantibody production and inflammation. CD38 is hi...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2019-12-01
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| coleção: | Journal of Translational Autoimmunity |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S258990901930022X |
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