Soluble Ectodomain of Neuroligin 1 Decreases Synaptic Activity by Activating Metabotropic Glutamate Receptor 2

Synaptic cell adhesion molecules represent important targets for neuronal activity-dependent proteolysis. Postsynaptic neuroligins (NLs) form trans-synaptic complexes with presynaptic neurexins (NXs). Both NXs and NLs are cleaved from the cell surface by metalloproteases in an activity-dependent man...

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Bibliografske podrobnosti

Principais autores:	Michelle D. Gjørlund, Eva M. M. Carlsen, Andreas B. Kønig, Oksana Dmytrieva, Anders V. Petersen, Jacob Jacobsen, Vladimir Berezin, Jean-François Perrier, Sylwia Owczarek
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2017-05-01
Serija:	Frontiers in Molecular Neuroscience
Teme:	synaptic activity proteolytic cleavage cell adhesion molecule hippocampus
Online dostop:	http://journal.frontiersin.org/article/10.3389/fnmol.2017.00116/full
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