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YIV-818-A: a novel therapeutic agent in prostate cancer management through androgen receptor downregulation, glucocorticoid receptor inhibition, epigenetic regulation, and enhancement of apalutamide, darolutamide, and enzalutamide efficacy

Introduction: Prostate cancer is the second leading cause of cancer death among men in the United States. Castration-Resistant Prostate Cancer (CRPC) often develops resistance to androgen deprivation therapy. Resistance in CRPC is often driven by AR variants and glucocorticoid receptor (GR). Thus, d...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Wing Lam, Mohammad Arammash, Wei Cai, Fulan Guan, Zaoli Jiang, Shwu-Huey Liu, Peikwen Cheng, Yung-Chi Cheng
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2023-10-01
Rangatū:Frontiers in Pharmacology
Ngā marau:
Urunga tuihono:https://www.frontiersin.org/articles/10.3389/fphar.2023.1244655/full
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