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Against Repurposing Methadone for Glioblastoma Therapy

Methadone, which is used as maintenance medication for outpatient treatment of opioid dependence or as an analgesic drug, has been suggested by preclinical in vitro and mouse studies to induce cell death and sensitivity to chemo- or radiotherapy in leukemia, glioblastoma, and carcinoma cells. These...

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Principais autores: Tatjana Vatter, Lukas Klumpp, Katrin Ganser, Nicolai Stransky, Daniel Zips, Franziska Eckert, Stephan M. Huber
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2020-06-01
סדרה:Biomolecules
נושאים:
ionizing radiation
flow cytometry
cell cycle regulation
clonogenic survival
colony formation assay
human glioblastoma cell lines
גישה מקוונת:https://www.mdpi.com/2218-273X/10/6/917
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