Increased apolipoprotein E and decreased TNF‐α in the cerebrospinal fluid of nondemented APOE‐ε4 carriers

Abstract Aim The ε4 allele of apolipoprotein E gene (APOE) is a well‐known risk factor of late‐onset Alzheimer's disease. However, little is known why this variant confers a risk for Alzheimer's disease. The aim of this study was to examine the influence of the APOE genotype on cerebrospinal fluid (...

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Główni autorzy:	Daimei Sasayama, Kotaro Hattori, Yuuki Yokota, Ryo Matsumura, Toshiya Teraishi, Sumiko Yoshida, Hiroshi Kunugi
Format:	Artigo
Język:	Inglês
Wydane:	Wiley 2020-06-01
Seria:	Neuropsychopharmacology Reports
Hasła przedmiotowe:	alzheimer disease apolipoproteins E biomarkers cerebrospinal fluid proteins tumor necrosis factor‐alpha
Dostęp online:	https://doi.org/10.1002/npr2.12110
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