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Metabolomics reveals the mechanism of action of meropenem and amikacin combined in the treatment of Pseudomonas aeruginosa

The treatment of Pseudomonas aeruginosa infection often involves the combined use of β-lactam and aminoglycoside antibiotics. In this study, we employed metabolomic analysis to investigate the mechanism responsible for the synergistic activities of meropenem/amikacin combination therapy against mult...

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Detalhes bibliográficos
Principais autores: Hai Yang, Zhen Huang, Jiali Yue, Jianqi Chen, Mingming Yu, Chengming Qu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-12-01
Colecção:Frontiers in Cellular and Infection Microbiology
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1327452/full
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