Cdx4 is dispensable for murine adult hematopoietic stem cells but promotes MLL-AF9-mediated leukemogenesis

Background Cdx4 is a homeobox gene essential for normal blood formation during embryonic development in the zebrafish, through activation of posterior Hox genes. However, its role in adult mammalian hematopoiesis has not been extensively studied and its requirement in leukemia associated with Hox ge...

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Hlavní autoři:	Sumin Koo, Brian J. Huntly, Yuan Wang, Jing Chen, Kristina Brumme, Brian Ball, Shannon L. McKinney-Freeman, Akiko Yabuuchi, Claudia Scholl, Dimple Bansal, Leonard I. Zon, Stefan Fröhling, George Q. Daley, D. Gary Gilliland, Thomas Mercher
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Ferrata Storti Foundation 2010-10-01
Edice:	Haematologica
On-line přístup:	https://haematologica.org/article/view/5747
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