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Clade-Specific Alterations within the HIV-1 Capsid Protein with Implications for Nuclear Translocation

The HIV-1 capsid (CA) protein has emerged as an attractive therapeutic target. However, all inhibitor designs and structural analyses for this essential HIV-1 protein have focused on the clade B HIV-1 (NL4-3) variant. This study creates, overproduces, purifies, and characterizes the CA proteins from...

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Autors principals: Alexej Dick, Megan E. Meuser, Simon Cocklin
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2022-05-01
Col·lecció:Biomolecules
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Accés en línia:https://www.mdpi.com/2218-273X/12/5/695
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