Natural Alkaloid Compounds as Inhibitors for Alpha-Synuclein Seeded Fibril Formation and Toxicity

The accumulation and aggregation of α-synuclein (α-syn) is the main pathologic event in Parkinson’s disease (PD), dementia with Lewy bodies, and multiple system atrophy. α-Syn-seeded fibril formation and its induced toxicity occupy a major role in PD pathogenesis. Thus, assessing compounds that inhi...

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Principais autores:	Simona S. Ghanem, Hend S. Fayed, Qi Zhu, Jia-Hong Lu, Nishant N. Vaikath, Janarthanan Ponraj, Said Mansour, Omar M. A. El-Agnaf
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2021-06-01
Series:	Molecules
Assuntos:	α-synuclein Parkinson’s disease seeded fibril formation
Acceso en liña:	https://www.mdpi.com/1420-3049/26/12/3736
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