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Integrating network pharmacology and experimental validation to decipher the mechanism of the Chinese herbal prescription modified Shen-Yan-Fang-Shuai formula in treating diabetic nephropathy

AbstractContext Diabetic nephropathy (DN) is the main cause of end-stage renal disease. Modified Shen-Yan-Fang-Shuai formula (M-SYFSF) has excellent clinical efficacy in treating diabetic kidney disease. However, the potential mechanism of M-SYFSF remains unknown.Objective To investigate the mechani...

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Principais autores: Borui Yu, Mengqi Zhou, Zhaocheng Dong, Huijuan Zheng, Yuxue Zhao, Jingwei Zhou, Chao Zhang, Fudong Wei, Guoyong Yu, Wei Jing Liu, Hongfang Liu, Yaoxian Wang
格式: Artigo
語言:Inglês
出版: Taylor & Francis Group 2023-12-01
叢編:Pharmaceutical Biology
主題:
Traditional Chinese medicine formula
protein-protein interaction network
MAPK signaling pathway
inflammation
在線閱讀:https://www.tandfonline.com/doi/10.1080/13880209.2023.2241521
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