The Hippo component YAP localizes in the nucleus of human papilloma virus positive oropharyngeal squamous cell carcinoma

Background HPV infection causes cervical cancer, mediated in part by the degradation of Scribble via the HPV E6 oncoprotein. Recently, Scribble has been shown to be an important regulator of the Hippo signaling cascade. Deregulation of the Hippo pathway induces an abnormal cellular transformation, e...

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Autori principali:	Faisal Alzahrani, Leanne Clattenburg, Shanmugam Muruganandan, Martin Bullock, Kaitlyn MacIsaac, Michael Wigerius, Blair A. Williams, M. Elise R. Graham, Matthew H. Rigby, Jonathan R. B. Trites, S. Mark Taylor, Christopher J. Sinal, James P. Fawcett, Robert D. Hart
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	SAGE Publishing 2017-01-01
Serie:	Journal of Otolaryngology - Head and Neck Surgery
Accesso online:	https://doi.org/10.1186/s40463-017-0187-1
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