Characterization and evaluation of gene fusions as a measure of genetic instability and disease prognosis in prostate cancer

Abstract Background Prostate cancer (PCa) is one of the most prevalent cancers worldwide. The clinical manifestations and molecular characteristics of PCa are highly variable. Aggressive types require radical treatment, whereas indolent ones may be suitable for active surveillance or organ-preservin...

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Detalhes bibliográficos

Principais autores:	Carolin Schimmelpfennig, Michael Rade, Susanne Füssel, Dennis Löffler, Conny Blumert, Catharina Bertram, Angelika Borkowetz, Dominik J. Otto, Sven-Holger Puppel, Pia Hönscheid, Ulrich Sommer, Gustavo B. Baretton, Ulrike Köhl, Manfred Wirth, Christian Thomas, Friedemann Horn, Markus Kreuz, Kristin Reiche
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-06-01
coleção:	BMC Cancer
Assuntos:	Biomarker Gene fusion Genomic instability Molecular diagnostic testing Molecular pathology Next-generation sequencing
Acesso em linha:	https://doi.org/10.1186/s12885-023-11019-6
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