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Novel monoclonal antibodies targeting the microtubule-binding domain of human tau.

Tauopathies including Alzheimer's disease and Progressive Supranuclear Palsy are a diverse group of progressive neurodegenerative disorders pathologically defined by inclusions containing aberrantly aggregated, post-translationally modified tau. The tau pathology burden correlates with neurodegenera...

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Bibliografische Detailangaben
Hauptverfasser: Cara L Croft, Brenda D Moore, Yong Ran, Paramita Chakrabarty, Yona Levites, Todd E Golde, Benoit I Giasson
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2018-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:http://europepmc.org/articles/PMC5880389?pdf=render
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