Decreased endomorphin-2 and opioidreceptor in the spinal cord are associated with painful diabetic neuropathy

Painful diabetic neuropathy (PDN) is one of the most common complications in the early stage of diabetes mellitus (DM). Endomorphin-2 (EM2) selectively activates the opioid receptor (MOR) and subsequently induces antinociceptive effects in the spinal dorsal horn. However, the effects of EM2-MOR in...

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Detalhes bibliográficos

Principais autores:	Zhen-Zhen Kou, Fa-Ping Wan, Yang Bai, Chun-Yu Li, Jia-Chen Hu, Guo-Tao Zhang, Zhang Ting, Tao Chen, Ya-Yun Wang, Hui Li, Yun-Qing Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2016-09-01
coleção:	Frontiers in Molecular Neuroscience
Assuntos:	Rats, Sprague-Dawley Painful Diabetic neuropathy endomorphin 2 spinal dorsal horn; opioid receptor
Acesso em linha:	http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00080/full
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