Damaging effect of ischemia on the development of retinal organoids derived from human embryonic stem cells

AIM: To explore the changes in early retinal development after the occurrence of ischemia. METHODS: Human retinal organoids (hROs) of day 18 or day 30 were treated with oxygen-glucose deprivation and reperfusion (OGD/R) to simulate the retinal ischemia. All hROs were maintained normally until day 60...

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Autores principales:	Yu-Han Yan, Hong-Yu Li, Li-Xiong Gao, Wen Li, Ling-Ping Zhao, Quan Zeng, Yu Luo, Tian-Tian Cui, Ru-Ge Zang, Zi Ye, Jia-Fei Xi, Wen Yue, Zhao-Hui Li
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Press of International Journal of Ophthalmology (IJO PRESS) 2025-08-01
Colección:	International Journal of Ophthalmology
Materias:	retinal diseases fetal ischemia oxygen-glucose deprivation and reperfusion human retinal organoids retinal ganglion cells
Acceso en línea:	http://ies.ijo.cn/en_publish/2025/8/20250803.pdf
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