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Photonic activation of plasminogen induced by low dose UVB.

Activation of plasminogen to its active form plasmin is essential for several key mechanisms, including the dissolution of blood clots. Activation occurs naturally via enzymatic proteolysis. We report that activation can be achieved with 280 nm light. A 2.6 fold increase in proteolytic activity was...

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Detalhes bibliográficos
Principais autores: Manuel Correia, Torben Snabe, Viruthachalam Thiagarajan, Steffen Bjørn Petersen, Sara R R Campos, António M Baptista, Maria Teresa Neves-Petersen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2015-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC4312030?pdf=render
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