Comparative Analysis of Single-cell and Single-nucleus RNA-sequencing in a Rabbit Model of Retinal Detachment-related Proliferative Vitreoretinopathy

Purpose: Proliferative vitreoretinopathy (PVR) is the most common cause of failure of retinal reattachment surgery, and the molecular changes leading to this aberrant wound healing process are currently unknown. Our ultimate goal is to study PVR pathogenesis by employing single-cell transcriptomics...

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Principais autores:	Clayton P. Santiago, PhD, MS, Megan Y. Gimmen, BSc, Yuchen Lu, BSc, Minda M. McNally, MS, Leighton H. Duncan, MA, BSc, Tyler J. Creamer, PhD, Linda D. Orzolek, MS, Seth Blackshaw, PhD, Mandeep S. Singh, MD, PhD
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2023-12-01
Colecção:	Ophthalmology Science
Assuntos:	Single cell RNA-sequencing Single nucleus RNA-sequencing Proliferative vitreoretinopathy Fibrosis
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2666914523000672
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