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Identification and validation of methylated PENK gene for early detection of bladder cancer using urine DNA

Abstract Background Early detection of bladder cancer (BCa) offers patients a favorable outcome and avoids the need for cystectomy. Development of an accurate and sensitive noninvasive BCa diagnostic test is imperative. DNA methylation is an early epigenetic event in the development of BCa. Certain...

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Auteurs principaux: Tae Jeong Oh, Eunkyung Lim, Bo-Ram Bang, Justin Junguek Lee, Yong Gil Na, Ju Hyun Shin, Jae Sung Lim, Ki Hak Song, Sungwhan An
Format: Artigo
Langue:Inglês
Publié: BMC 2022-11-01
Collection:BMC Cancer
Sujets:
Bladder cancer
Methylation
Noninvasive
PENK
Urine sediment
Accès en ligne:https://doi.org/10.1186/s12885-022-10275-2
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