Exploring the Mechanism of Sempervirine Inhibiting Glioblastoma Invasion Based on Network Pharmacology and Bioinformatics

<b>Background</b>: Invasion is an important characteristic of the malignancy of glioblastoma (GBM) and a significant prognostic factor. Sempervirine (SPV), a yohimbine-type alkaloid, has been proven to inhibit GBM cells proliferation in previous research and found to have a potential effect in anti-...

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Autores principales:	Bingqiang Zhang, Wenyi Wang, Yu Song, Huixian Chen, Xinxin Lin, Jingjing Chen, Ying Chen, Jinfang Huang, Desen Li, Shuisheng Wu
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2024-10-01
Colección:	Pharmaceuticals
Materias:	glioblastoma sempervirine invasion AKT phosphorylation matrix metalloproteinases
Acceso en línea:	https://www.mdpi.com/1424-8247/17/10/1318
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