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Osteoblasts secrete Cxcl9 to regulate angiogenesis in bone

Abstract Communication between osteoblasts and endothelial cells (ECs) is essential for bone turnover, but the molecular mechanisms of such communication are not well defined. Here we identify Cxcl9 as an angiostatic factor secreted by osteoblasts in the bone marrow microenvironment. We show that Cx...

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Bibliografiske detaljer
Principais autores: Bin Huang, Wenhao Wang, Qingchu Li, Zhenyu Wang, Bo Yan, Zhongmin Zhang, Liang Wang, Minjun Huang, Chunhong Jia, Jiansen Lu, Sichi Liu, Hongdong Chen, Mangmang Li, Daozhang Cai, Yu Jiang, Dadi Jin, Xiaochun Bai
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2016-12-01
Serier:Nature Communications
Online adgang:https://doi.org/10.1038/ncomms13885
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