Variations in Local Calcium Signaling in Adjacent Cardiac Myocytes of the Intact Mouse Heart Detected with Two-Dimensional Confocal Microscopy

Dyssynchronous local Ca release within individual cardiac myocytes has been linked to cellular contractile dysfunction. Differences in Ca kinetics in adjacent cells may also provide a substrate for inefficient contraction and arrhythmias. In a new approach we quantify variation in local Ca transient...

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Bibliografski detalji

Glavni autori:	Karin P Hammer, Felix eHohendanner, Lothar A Blatter, Burkert M Pieske, Frank R. Heinzel
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2015-01-01
Serija:	Frontiers in Physiology
Teme:	Excitation Contraction Coupling cardiac myocytes intercellular communication calcium cycling Langendorff perfused heart Whole Heart
Online pristup:	http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00517/full
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