Baseline gut microbiome and metabolome profiles predict weight loss after a structured lifestyle intervention

Abstract Background Obesity remains a global health challenge, and responses to lifestyle-based weight-loss interventions are heterogeneous. Here, we evaluate a one-year structured lifestyle program in 50 adults with obesity (mean BMI 42 ± 7.0 kg/m2), integrating clinical, microbiome, and metabolomi...

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Hauptverfasser:	Benjamin Seethaler, Maryam Basrai, Nathalie M. Delzenne, Jens Walter, Nguyen K. Nguyen, Stephan C. Bischoff
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2026-08-01
Schriftenreihe:	Microbiome
Schlagworte:	Obesity Weight-loss Microbiome Metabolome Gut barrier
Online-Zugang:	https://doi.org/10.1186/s40168-026-02501-x
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