Generation of chimeric chickens resistant to infection by avian leukemia virus subgroups A, B, D, E, and K through primordial germ cells

Avian leukosis virus (ALVs), an oncogenic retrovirus, induces immunosuppression and various tumors in chickens, posing a severe global threat to poultry health and causing substantial economic losses. Natural resistance alleles, notably tvar2 and tvbr3, confer genetic resistance to specific ALV subg...

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Hauptverfasser:	Gengsheng Xiao, Weiguo Chen, Xiaoling Chen, Ying Huang, Tingxi Pan, Sheng Chen, Yongsen Wen, Hongxin Li, Xinheng Zhang, Qingmei Xie
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2026-05-01
Schriftenreihe:	Poultry Science
Schlagworte:	Avian leukemia virus Chimera chicken Microinjection Primordial germ cell
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S0032579126002695
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