Spatial Transcriptomics Unveils Landscape of Resistance to Concurrent Chemo‐Radiotherapy in Hypopharyngeal Squamous Cell Carcinoma: The Role of SPP1+ Macrophages

ABSTRACT Background Hypopharyngeal squamous cell carcinoma (SCC) is an aggressive malignancy with a poor prognosis, particularly in advanced stages. Concurrent chemoradiotherapy (CCRT) is frequently employed to preserve the larynx, but resistance to CCRT remains a significant clinical challenge. Und...

Descripción completa

Detalles Bibliográficos

Autores principales:	Jungyoon Ohn, Sungwoo Bae, Hongyoon Choi, Jiwon Koh, In Gul Kim, Eun‐Jae Chung, Kwon Joong Na
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Wiley 2026-01-01
Colección:	Cancer Medicine
Materias:	concurrent chemoradiotherapy resistance hypopharyngeal squamous cell carcinoma macrophage secreted phosphoprotein 1 spatial transcriptomics tumor microenvironment
Acceso en línea:	https://doi.org/10.1002/cam4.71493
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!