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The immunoregulatory role of monocytes and thrombomodulin in myelodysplastic neoplasms

Myelodysplastic neoplasms (MDS) are clonal disorders of the myeloid lineage leading to peripheral blood cytopenias. Dysregulation of innate immunity is hypothesized to be a potent driver of MDS. A recent study revealed increased thrombomodulin (TM) expression on classical monocytes in MDS, which was...

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Autors principals: Luca L. G. Janssen, Nathalie van Leeuwen-Kerkhoff, Theresia M. Westers, Tanja D. de Gruijl, Arjan A. van de Loosdrecht
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2024-07-01
Col·lecció:Frontiers in Oncology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fonc.2024.1414102/full
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