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Genome-wide identification of somatic aberrations from paired normal-tumor samples.

Genomic copy number alteration and allelic imbalance are distinct features of cancer cells, and recent advances in the genotyping technology have greatly boosted the research in the cancer genome. However, the complicated nature of tumor usually hampers the dissection of the SNP arrays. In this stud...

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Autori principali: Ao Li, Yuanning Liu, Qihong Zhao, Huanqing Feng, Lyndsay Harris, Minghui Wang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2014-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC3907544?pdf=render
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