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Integrating p53-associated genes and infiltrating immune cell characterization as a prognostic biomarker in multiple myeloma

Background: Tumor genetic anomalies and immune dysregulation are pivotal in the progression of multiple myeloma (MM). Accurate patient stratification is essential for effective MM management, yet current models fail to comprehensively incorporate both molecular and immune profiles. Methods: We exami...

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Main Authors: Jun-Ting Lv, Yu-Tian Jiao, Xin-Le Han, Yang-Jia Cao, Xu-Kun Lv, Jun Du, Jian Hou
Format: Artigo
Language:Inglês
Published: Elsevier 2024-04-01
Series:Heliyon
Subjects:
Multiple myeloma (MM)
Stratification model
p53 signaling pathway
Immune microenvironment
Immune checkpoints
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024061541
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