Targeted Inactivation of Bax Reveals a Subtype-Specific Mechanism of Cajal-Retzius Neuron Death in the Postnatal Cerebral Cortex

Cajal-Retzius cells (CRs), the first-born neurons in the developing cerebral cortex, coordinate crucial steps in the construction of functional circuits. CRs are thought to be transient, as they disappear during early postnatal life in both mice and humans, where their abnormal persistence is associ...

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Detalhes bibliográficos

Principais autores:	Fanny Ledonne, David Orduz, Judith Mercier, Lisa Vigier, Elisabeth A. Grove, Fadel Tissir, Maria Cecilia Angulo, Alessandra Pierani, Eva Coppola
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2016-12-01
coleção:	Cell Reports
Assuntos:	Cajal-Retzius cells Bax death distribution postnatal cerebral cortex transient neurons immature circuits
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211124716316485
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