Improving the EMA Binding Test by Using Commercially Available Fluorescent Beads

Hereditary spherocytosis (HS) is a common anemia caused by germline mutations in red blood cell cytoskeleton proteins. The flow cytometry-based eosin-5′-maleimide (EMA) binding test is most frequently employed for reliable diagnostics. To perform this test, a number of healthy and ideally also age-m...

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Auteurs principaux:	Andreas Glenthøj, Alaa Sharfo, Christian Brieghel, Amina Nardo-Marino, Henrik Birgens, Jesper Brix Petersen
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2020-09-01
Collection:	Frontiers in Physiology
Sujets:	hereditary spherocytosis EMA binding test hemolysis anemia membranopathy ektacytometry
Accès en ligne:	https://www.frontiersin.org/article/10.3389/fphys.2020.569289/full
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