Huperzine A Regulates the Physiological Homeostasis of Amyloid Precursor Protein Proteolysis and Tau Protein Conformation—A Computational and Experimental Investigation

The beneficial actions of the natural compound Huperzine A (Hup A) against age-associated learning and memory deficits promote this compound as a nootropic agent. Alzheimer’s disease (AD) pathophysiology is characterized by the accumulation of amyloid beta (Aβ). Toxic Aβ oligomers account for the co...

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Detalhes bibliográficos

Principais autores:	Suwakon Wongjaikam, Chutikorn Nopparat, Parichart Boontem, Jiraporn Panmanee, Nopporn Thasana, Mayuri Shukla, Piyarat Govitrapong
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2024-07-01
coleção:	Biology
Assuntos:	Huperzine A Alzheimer’s disease amyloid beta amyloid precursor protein β-site amyloid precursor protein cleaving enzyme 1 presenilin 1
Acesso em linha:	https://www.mdpi.com/2079-7737/13/7/518
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