Thrombomodulin in disseminated intravascular coagulation and other critical conditions—a multi-faceted anticoagulant protein with therapeutic potential

Abstract Thrombomodulin plays a vital role in maintaining intravascular patency due to its anticoagulant, antiinflammatory, and cytoprotective properties. However, under pathological conditions such as sepsis and systemic inflammation, endothelial thrombomodulin expression is downregulated and its f...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Takashi Ito, Jecko Thachil, Hidesaku Asakura, Jerrold H. Levy, Toshiaki Iba
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	BMC 2019-08-01
Sarja:	Critical Care
Aiheet:	Recombinant thrombomodulin Disseminated intravascular coagulation (DIC) Coagulopathy Randomized controlled trial Bleeding Sepsis
Linkit:	http://link.springer.com/article/10.1186/s13054-019-2552-0
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