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Assessing olaparib efficacy in U.S. Veterans with metastatic prostate cancer utilizing a time-indifferent g-rate method ideal for real-world analysesResearch in context

Summary: Background: We aimed to assess real-world efficacy of the PARP inhibitor, olaparib, in US Veterans with metastatic prostate cancer (mPC) by leveraging the national data repository and evaluate a novel approach to assess treatment efficacy in tumors considered rare or harboring rare mutatio...

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Principais autores: Harshraj Leuva, Mengxi Zhou, Nader Jamaleddine, Mina Meseha, Izak Faiena, Yeun-Hee Anna Park, Glen McWilliams, Carol Luhrs, Kara N. Maxwell, Daniel Von Hoff, Susan E. Bates, Tito Fojo
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2024-09-01
coleção:EBioMedicine
Assuntos:
Homologous recombination repair
Olaparib
Real-world data
g-rate
Efficacy evaluation
Prostate cancer
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2352396424003244
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