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Mitochondrial Quality Control and Cellular Proteostasis: Two Sides of the Same Coin

Mitochondrial dysfunction is a hallmark of cardiac pathophysiology. Defects in mitochondrial performance disrupt contractile function, overwhelm myocytes with reactive oxygen species (ROS), and transform these cellular powerhouses into pro-death organelles. Thus, quality control (QC) pathways aimed...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Justin M. Quiles, Åsa B. Gustafsson
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2020-05-01
Saila:Frontiers in Physiology
Gaiak:
Sarrera elektronikoa:https://www.frontiersin.org/article/10.3389/fphys.2020.00515/full
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