Dupilumab Reduces Urticaria Activity, Itch, and Hives in Patients with Chronic Spontaneous Urticaria Regardless of Baseline Serum Immunoglobulin E Levels

Abstract Introduction In chronic spontaneous urticaria (CSU), interleukin (IL)-4 and IL-13 may promote mast cell activation directly via IL-4 receptor expression, or indirectly via upregulated immunoglobulin E (IgE) production. Dupilumab significantly improved CSU signs and symptoms in the phase 3,...

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Principais autores:	Marcus Maurer, Thomas B. Casale, Sarbjit S. Saini, Moshe Ben-Shoshan, Elizabeth Laws, Jennifer Maloney, Deborah Bauer, Allen Radin, Melanie Makhija
Format:	Artigo
Jezik:	Inglês
Izdano:	Adis, Springer Healthcare 2024-07-01
Serija:	Dermatology and Therapy
Teme:	Biomarker Chronic spontaneous urticaria CSU Dupilumab Immunoglobulin E IgE
Online dostop:	https://doi.org/10.1007/s13555-024-01231-y
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