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Effect of prophylactic subcutaneous unfractionated heparin on the maternal sFlt-1/PlGF ratio: a retrospective cohort study

Abstract Background The ratio of soluble fms-like tyrosine kinase-1 (sFlt-1) to placental growth factor (PlGF) is widely used to assess the risk of preeclampsia. However, heparin can transiently increase the level of circulating sFlt-1, making it unclear whether prophylactic subcutaneous unfractiona...

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Príomhchruthaitheoirí: Yuri Yoshida, Takayuki Iriyama, Yu Ariyoshi, Yuji Ida, Eriko Yano, Haruka Matsui, Kensuke Suzuki, Ayako Hashimoto, Mari Ichinose, Masatake Toshimitsu, Seisuke Sayama, Kenbun Sone, Osamu Wada-Hiraike, Keiichi Kumasawa, Miyuki Harada, Yasushi Hirota
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: BMC 2026-05-01
Sraith:BMC Pregnancy and Childbirth
Ábhair:
Heparin
Unfractionated heparin
sFlt-1
PlGF
Preeclampsia
Rochtain ar líne:https://doi.org/10.1186/s12884-026-09306-8
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