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MOHITO, a novel mouse cytokine-dependent T-cell line, enables studies of oncogenic signaling in the T-cell context

The mouse pro-B cell line Ba/F3 has gained major interest as a model system to investigate oncogenic tyrosine kinases and to determine the efficacy of kinase inhibitors. While Ba/F3 cells are suitable to study oncogenic kinases derived from various cell types, the signaling networks in Ba/F3 cells a...

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Détails bibliographiques
Auteurs principaux: Maria Kleppe, Nicole Mentens, Thomas Tousseyn, Iwona Wlodarska, Jan Cools
Format: Artigo
Langue:Inglês
Publié: Ferrata Storti Foundation 2011-05-01
Collection:Haematologica
Accès en ligne:https://haematologica.org/article/view/5977
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