A neutralizing single-domain antibody that targets the trimer interface of the human metapneumovirus fusion protein

ABSTRACTHuman metapneumovirus (hMPV) is a leading cause of viral lower respiratory tract disease in children and adults. The hMPV fusion protein F is a trimeric class I fusion protein that is initially synthesized as a precursor (F0) and requires proteolytic activation by a host cell protease to gen...

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Manylion Llyfryddiaeth

Prif Awduron:	Marlies Ballegeer, Revina C. van Scherpenzeel, Teresa Delgado, Maria Iglesias-Caballero, Blanca García Barreno, Shubham Pandey, Scott A. Rush, Joost A. Kolkman, Vicente Mas, Jason S. McLellan, Xavier Saelens
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	American Society for Microbiology 2024-01-01
Cyfres:	mBio
Pynciau:	human metapneumovirus single-domain antibody fusion protein structure
Mynediad Ar-lein:	https://journals.asm.org/doi/10.1128/mbio.02122-23
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