In vitro antiproliferative activity, docking study, and plausible mode of action of (+)-2,2′-epicytoskyrin A against breast cancer MCF-7 and T47D cell lines

Abstract Background The endophytic fungus Diaporthe sp. GNBP-10 has been reported to produce metabolite bis-anthraquinone (+)-2,2′-epicytoskyrin A in high titers. In this study, we evaluated the potential of this metabolite as an anti-breast cancer agent by conducting antiproliferative activity stud...

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Prif Awduron:	Agus Budiawan Naro Putra, Kartika Dyah Palupi, Ahmad Fathoni, Listiana Oktavia, Endah Puji Septisetyani, Arif Nurkanto, Praptiwi Praptiwi, Dewi Wulansari, Adi Santoso, Dwinna Rahmi, Andria Agusta
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	SpringerOpen 2025-05-01
Cyfres:	Beni-Suef University Journal of Basic and Applied Sciences
Pynciau:	(+)-2,2′-Epicytoskyrin A Antiproliferative Diaporthe sp. GNBP-10 Uncaria gambier
Mynediad Ar-lein:	https://doi.org/10.1186/s43088-025-00632-y
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