The salivary microbiome as a diagnostic biomarker of periodontitis: a 16S multi-batch study before and after the removal of batch effects

IntroductionMicrobiome-based clinical applications that improve diagnosis related to oral health are of great interest to precision dentistry. Predictive studies on the salivary microbiome are scarce and of low methodological quality (low sample sizes, lack of biological heterogeneity, and absence o...

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Autori principali:	Alba Regueira-Iglesias, Berta Suárez-Rodríguez, Triana Blanco-Pintos, Marta Relvas, Manuela Alonso-Sampedro, Carlos Balsa-Castro, Inmaculada Tomás
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2024-07-01
Serie:	Frontiers in Cellular and Infection Microbiology
Soggetti:	periodontal diseases saliva microbiome 16S rRNA gene next-generation sequencing batch effects
Accesso online:	https://www.frontiersin.org/articles/10.3389/fcimb.2024.1405699/full
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