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A human-serum-free medium can induce more infectious P. falciparum gametocytes than a conventional human-serum-containing medium

Abstract Malaria remains a global health problem, and the standard membrane feeding assay (SMFA) is a key functional assay for development of new interventions to stop malaria transmission from human to mosquito. For SMFA, media with ~ 10% of human serum has been used for infectious gametocyte cultu...

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Principais autores: Kazutoyo Miura, Bingbing Deng, Ragavan Varadharajan Suresh, Yonas T. Gebremicale, Luwen Zhou, Thao P. Pham, Kyle Roche, Ababacar Diouf, Jonathan F. Lovell, Jean-Philippe Julien, Carole A. Long
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2024-09-01
Serier:Scientific Reports
Fag:
Plasmodium Falciparum: malaria
Gametocyte
Gametocyte culture
Serum free
Standard membrane-feeding assay
SMFA
Online adgang:https://doi.org/10.1038/s41598-024-73843-5
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